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Endocrine Abstracts

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ea0081p606 | Diabetes, Obesity, Metabolism and Nutrition | ECE2022

The ecology of the microbiome in children with congenital generalized lipodystrophy type 4 (CGL4) is quickly modified after metreleptin treatment

Daffara Tommaso , Mancioppi Valentina , Caputo Marina , Bellone Simonetta , Massa Nadia , Caramaschi Alice , Mignone Flavio , Romanisio Martina , Rabbone Ivana , Giordano Mara , Aimaretti Gianluca , Bona Elisa , Prodam Flavia

Introduction: Lipodystrophy syndromes are characterized by a progressive metabolic impairment secondary to adipose tissue dysfunction and genetic background. The role of microbiota is still uninvestigated.Objective: Evaluate the gut microbiome ecology in relation to dietary and clinical parameters in two infant siblings with congenital generalized lipodystrophy type 4 (CGL4) before and after treatment with recombinant leptin.Method...
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ea0073aep166 | Diabetes, Obesity, Metabolism and Nutrition | ECE2021

The ecology of the microbiome in children with obesity is associated to insulin resistance anddiet composition

Ricotti Roberta , Archero Francesca , Landoni Valentina , Mancioppi Valentina , Caputo Marina , Bellone Simonetta , Solito Arianna , Antoniotti Valentina , Gamalero Elisa , Massa Nadia , Mignone Flavio , Cavaletto Maria , Agosti Emanuela , Bona Elisa , Prodam Flavia

IntroductionIn the pediatric population, the progression of obesity-related diseases can be delayed or prevented through lifestyle changes, including the promotion of a Mediterranean-like dietary (MD) pattern.ObjectiveWe aimed to evaluate the gut microbiome ecology in relation to dietary and clinical parameters in the pediatric subjects with obesity recruited at baseline in a protocol on an educational traini...
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Published by BioScientifica

Endocrine Abstracts
ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
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